RAD23B anticorps

N° du produit ABIN7252582

Cet anticorps Lapin Polyclonal détecte spécifiquement RAD23B dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour RAD23B anticorps (ABIN7252582)

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RAD23B anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human RAD23B

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: RAD23B

Sujet: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 43 kDa

UniProt: P54727

Pathways: Réparation de l'ADN